Has anybody deployed their own database cluster across data centers in a region?

I have been considered a MariaDB Cluster (MaxScale or Galera) with a node in NYC1, NYC2 and NYC3. With vpc peering this seems like a reasonable approach for a HA solution. But…

• With MaxScale write connection are going to frequently cross between data centers to hit the primary and read could cross between data centers as well.
• With Galera only the synchronous replication will cross data centers, but writes will block until the data is certified on all three servers.

The latency looks pretty good between datacenter, but I cannot replicate the full load or our solution in order to get a clear understanding of the performance implact. I have tested to make sure it works and performance for test transactions seems pretty good.

I’m just reaching out to see if anybody else has already attempted this and might have some knowledge to share.